Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 7/20 | 0.39 |
| ▸ | FNTB | P49356 | 7/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PEX14 | O75381 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247262 | 1.00 | POLB (0.47) | POLBFNTAFNTBPGGT1BIDO1 | |
| SCHEMBL9244403 | 0.91 | POLB (0.45) | POLBFNTAFNTBPGGT1BIDO1 | |
| SCHEMBL9244519 | 0.84 | GAA (0.38) | POLBOPRM1OPRD1OPRK1 | |
| SCHEMBL9244509 | 0.84 | GAA (0.38) | POLBOPRM1OPRD1OPRK1 | |
| SCHEMBL9567637 | 0.84 | POLB (0.47) | POLBFNTAFNTBPGGT1BIDO1 | |
| SCHEMBL9244604 | 0.83 | CALCA (0.36) | CYP19A1 | |
| SCHEMBL9244600 | 0.83 | CALCA (0.36) | CYP19A1 | |
| SCHEMBL9244542 | 0.81 | POLB (0.47) | POLBFNTAFNTBPGGT1BIDO1 | |
| SCHEMBL9244520 | 0.81 | POLB (0.47) | POLBFNTAFNTBPGGT1BIDO1 | |
| SCHEMBL9241754 | 0.80 | EPHX1 (0.36) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449785-A | Fungicides with triazole groups | HOFFMANN-LA ROCHE INC. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0524439-A1 | Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-01-27 | — | — | EP | disclosed |