Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 5/20 | 0.34 |
| ▸ | FNTB | P49356 | 5/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244403 | 0.86 | POLB (0.45) | POLBSLC18A2CYP19A1TBXAS1IDO1 | |
| SCHEMBL9247259 | 0.84 | POLB (0.47) | POLBCYP19A1TBXAS1IDO1FNTA | |
| SCHEMBL9247262 | 0.84 | POLB (0.47) | POLBCYP19A1TBXAS1IDO1FNTA | |
| SCHEMBL9241703 | 0.84 | CYP19A1 (0.47) | POLBCYP19A1TBXAS1IDO1FNTA | |
| SCHEMBL9567750 | 0.84 | GAA (0.38) | POLBSLC18A2SLC6A2SLC6A4 | |
| SCHEMBL9247365 | 0.80 | SLC18A2 (0.42) | SLC18A2SLC6A2SLC6A4 | |
| SCHEMBL8714592 | 0.76 | TBXAS1 (0.40) | CYP19A1TBXAS1 | |
| SCHEMBL9244400 | 0.71 | CYP19A1 (0.45) | POLBCYP19A1TBXAS1IDO1FNTA | |
| SCHEMBL9243685 | 0.71 | CALCA (0.35) | CYP19A1CYP11B1CYP17A1 | |
| SCHEMBL9244604 | 0.70 | CALCA (0.36) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524439-A1 | Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-01-27 | — | — | EP | disclosed |