Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594533 | 0.98 | TGFBR1 (0.37) | TGFBR1ADAMTS4CA2CA1TSHR | |
| SCHEMBL10594525 | 0.98 | TGFBR1 (0.37) | TGFBR1ADAMTS4CA2CA1TSHR | |
| SCHEMBL9247359 | 0.96 | TGFBR1 (0.36) | TGFBR1ADAMTS4CA2CA1TSHR | |
| SCHEMBL10879686 | 0.81 | TGFBR1 (0.35) | TGFBR1TSHRNR4A2SMN1; SMN2MME | |
| SCHEMBL2561637 | 0.81 | TGFBR1 (0.35) | TGFBR1TSHRNR4A2SMN1; SMN2MME | |
| SCHEMBL7760488 | 0.79 | MME (0.34) | NR4A2SMN1; SMN2SLC6A5MMEACE | |
| SCHEMBL454664 | 0.79 | MME (0.34) | NR4A2SMN1; SMN2SLC6A5MMEACE | |
| SCHEMBL3442583 | 0.76 | ALDH1A1 (0.36) | TSHRSMN1; SMN2MMEACECPA1 | |
| SCHEMBL596423 | 0.76 | ALDH1A1 (0.36) | TSHRSMN1; SMN2MMEACECPA1 | |
| SCHEMBL667846 | 0.76 | ALDH1A1 (0.41) | MMEACECPA1ACE2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403902-A | Addition polymerization of water soluble monomers, at least one alkenyl azlactone and crosslinker; useful as complexing agents, supports of chromatography, enzymatic components | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-04-04 | — | — | US | disclosed |
| US-5336742-A | Azlactone-functional polymer supports, e.g. beads; complexing agents, catalysts and biological reagent for proteins and enzymes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-08-09 | — | — | US | disclosed |
| US-5292840-A | Acrylic amide adducts | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0354909-B1 | VARIABLE CROSSLINKED POLYMERIC SUPPORTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-01-02 | — | — | EP | disclosed |
| EP-0354909-A1 | VARIABLE CROSSLINKED POLYMERIC SUPPORTS. | MINNESOTA MINING & MFG (US) | 1990-02-21 | — | — | EP | disclosed |
| US-4871824-A | AZLACTONE FUNCTIONAL POLYMER BEADS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-10-03 | — | — | US | disclosed |
| WO-1988007062-A1 | VARIABLE CROSSLINKED POLYMERIC SUPPORTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-09-22 | — | — | WO | disclosed |
| US-4737560-A | AZLACTONE FUNCTIONAL | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-04-12 | — | — | US | disclosed |