Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246203 | 0.84 | CYP19A1 (0.46) | CYP19A1CYP11B1CYP11B2TBXAS1CYP2D6 | |
| SCHEMBL9246480 | 0.83 | REN (0.42) | CYP19A1HRH3POLB | |
| SCHEMBL9246493 | 0.83 | REN (0.42) | CYP19A1HRH3POLB | |
| SCHEMBL9241703 | 0.81 | CYP19A1 (0.47) | CYP19A1CYP11B1CYP11B2TBXAS1CYP2D6 | |
| SCHEMBL9243845 | 0.79 | HRH3 (0.40) | HRH3 | |
| SCHEMBL9243839 | 0.79 | HRH3 (0.40) | HRH3 | |
| SCHEMBL8718767 | 0.79 | HRH3 (0.40) | HRH3 | |
| SCHEMBL9247644 | 0.79 | CYP19A1 (0.40) | CYP19A1CYP11B1CYP11B2TBXAS1POLB | |
| SCHEMBL9247649 | 0.75 | BCHE (0.35) | HRH3 | |
| SCHEMBL9246183 | 0.75 | CYP19A1 (0.38) | CYP19A1CYP11B1CYP11B2TBXAS1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449785-A | Fungicides with triazole groups | HOFFMANN-LA ROCHE INC. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0524439-A1 | Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-01-27 | — | — | EP | disclosed |