Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 10/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9241763 | 0.86 | LTB4R (0.32) | CYP19A1POLBCYP26A1TBXAS1 | |
| SCHEMBL9244481 | 0.84 | REN (0.37) | POLBCYP26A1CYP3A4HSD11B1 | |
| SCHEMBL9247644 | 0.83 | CYP19A1 (0.40) | CYP19A1POLBCYP26A1TBXAS1HSD11B1 | |
| SCHEMBL9244406 | 0.82 | CYP19A1 (0.38) | CYP19A1POLBCYP26A1TBXAS1CYP3A4 | |
| SCHEMBL8719427 | 0.81 | UGT2B7 (0.38) | CYP3A4HSD11B1KCNH2 | |
| SCHEMBL9246203 | 0.79 | CYP19A1 (0.46) | CYP19A1POLBTBXAS1CYP11B1CYP11B2 | |
| SCHEMBL8714349 | 0.77 | HSD11B1 (0.35) | HSD11B1KCNH2 | |
| SCHEMBL9247657 | 0.75 | CYP19A1 (0.49) | CYP19A1POLBTBXAS1CYP11B1CYP11B2 | |
| SCHEMBL9244337 | 0.74 | PDE10A (0.35) | CYP19A1 | |
| SCHEMBL9244356 | 0.74 | PDE10A (0.35) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449785-A | Fungicides with triazole groups | HOFFMANN-LA ROCHE INC. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0524439-A1 | Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-01-27 | — | — | EP | disclosed |