Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.37 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255486 | 0.94 | EHMT2 (0.41) | EHMT2ENPP2RAB9AALDH1A1HPGD | |
| SCHEMBL9253406 | 0.88 | EHMT2 (0.40) | EHMT2ENPP2RAB9AALDH1A1HPGD | |
| SCHEMBL9254678 | 0.87 | EHMT2 (0.47) | EHMT2ENPP2RAB9AALDH1A1HPGD | |
| SCHEMBL9251437 | 0.86 | ENPP2 (0.43) | EHMT2ENPP2RAB9AALDH1A1HPGD | |
| SCHEMBL9252259 | 0.86 | EHMT2 (0.43) | EHMT2ENPP2ALDH1A1HPGDMAPT | |
| SCHEMBL9252687 | 0.85 | JAK2 (0.45) | EHMT2ENPP2ALDH1A1HPGDMAPT | |
| SCHEMBL9248676 | 0.83 | ALDH1A1 (0.39) | EHMT2ENPP2RAB9AALDH1A1HPGD | |
| SCHEMBL9245966 | 0.83 | F10 (0.37) | EHMT2ENPP2ALDH1A1HPGDMAPT | |
| SCHEMBL9245485 | 0.82 | PTGER4 (0.48) | EHMT2ENPP2RAB9AALDH1A1HPGD | |
| SCHEMBL9247664 | 0.82 | PTGER4 (0.43) | EHMT2ENPP2RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |