Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.68 |
| ▸ | FNTA | P49354 | 2/20 | 0.42 |
| ▸ | FNTB | P49356 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 7/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546697 | 1.00 | TACR1 (0.68) | TACR1FNTAFNTBMEN1CYP3A4 | |
| SCHEMBL7885109 | 1.00 | TACR1 (0.68) | TACR1FNTAFNTBMEN1CYP3A4 | |
| SCHEMBL8957032 | 0.90 | TACR1 (0.66) | TACR1FNTAFNTBMEN1CYP3A4 | |
| SCHEMBL8956775 | 0.89 | TACR1 (0.54) | TACR1FNTAFNTBMEN1CYP3A4 | |
| SCHEMBL8873936 | 0.88 | TACR1 (0.52) | TACR1MEN1KMT2AALKRORC | |
| SCHEMBL8874860 | 0.88 | TACR1 (0.52) | TACR1MEN1KMT2AALKRORC | |
| SCHEMBL8956761 | 0.88 | TACR1 (0.52) | TACR1TSHRRORCPDK2USP30 | |
| SCHEMBL9244693 | 0.87 | TACR1 (0.49) | TACR1TSHRRORCUSP30 | |
| SCHEMBL8956952 | 0.87 | TACR1 (0.49) | TACR1TSHRRORCUSP30 | |
| SCHEMBL8545144 | 0.84 | TACR1 (0.48) | TACR1FNTAFNTBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463077-A | Exhibit substance P antagonist activity | RHONE-POULENC RORER S.A. (FR) | 1995-10-31 | — | — | US | disclosed |