Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | AR | P10275 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15677159 | 0.94 | KMT2A (0.60) | HTTHIF1AARKMT2AMEN1 | |
| SCHEMBL19275254 | 0.92 | HTT (0.53) | HTTHIF1AARKMT2AMEN1 | |
| SCHEMBL22043203 | 0.92 | HTT (0.57) | HTTHIF1AARKMT2AMEN1 | |
| SCHEMBL17036998 | 0.90 | LMNA (0.56) | HTTHIF1AARKMT2AMEN1 | |
| SCHEMBL12031009 | 0.90 | HTT (0.65) | HTTHIF1AARKMT2AMEN1 | |
| SCHEMBL12789564 | 0.87 | HTT (0.65) | HTTHIF1AARKMT2AMEN1 | |
| Ether SCHEMBL6535226 | 0.86 | HTT (0.51) | HTTHIF1AARKMT2AMEN1 | |
| SCHEMBL9248076 | 0.86 | HTT (0.61) | HTTHIF1AARKMT2AMEN1 | |
| SCHEMBL17345235 | 0.86 | KMT2A (0.67) | HTTHIF1AARKMT2AMEN1 | |
| SCHEMBL3416414 | 0.86 | HTT (0.60) | HTTHIF1AARKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915796-A1 | PROPYL-PHENYL-ETHER DERIVATIVE AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT, AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | Seiwa Kasei Company, Limited (JP) | 2015-09-09 | — | — | EP | disclosed |
| US-20150238401-A1 | PROPYL-PHENYL-ETHER DERIVATIVE, AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | SEIWA KASEI COMPANY, LIMITED (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20150238401-A1 | PROPYL-PHENYL-ETHER DERIVATIVE, AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | SEIWA KASEI COMPANY, LIMITED (JP) | 2015-08-27 | — | — | US | disclosed |
| WO-2014069555-A1 | PROPYL-PHENYL-ETHER DERIVATIVE AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT, AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | 株式会社成和化成 (JP) | 2014-05-08 | — | — | WO | disclosed |
| EP-0365479-B1 | Curable epoxide resin compositions | CIBA GEIGY AG (CH) | 1995-12-20 | — | — | EP | disclosed |
| EP-0388359-B1 | IMIDAZOLINE COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-05-12 | — | — | EP | disclosed |
| US-5152862-A | Curing accelerators for epoxide resins | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-5021513-A | Phenolic resin and aliphatic polyamine | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| US-4997951-A | Cure accelerator for epoxy resin | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4977214-A | Nitrogen-containing latent hardener, polyamine promoters; adhesives, sealants, coatings | CIBA-GEIGY CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0365479-A2 | Curable epoxide resin compositions | CIBA-GEIGY AG (CH) | 1990-04-25 | — | — | EP | disclosed |
| US-4284574-A | MOLDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1981-08-18 | — | — | US | disclosed |
| EP-0022073-A1 | Diglycidyl ethers of di-secondary alcohols, their preparation and their use | CIBA-GEIGY AG (CH) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150238401-A1 | PROPYL-PHENYL-ETHER DERIVATIVE, AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | TYR, MITF, MC1R | HTT 2785/4885HIF1A 2044/4885AR 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.