Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.57 |
| ▸ | ESR1 | P03372 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757648 | 0.85 | ESR2 (0.57) | ESR2ESR1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL29290927 | 0.85 | ESR2 (0.61) | ESR2ESR1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL29490659 | 0.83 | ESR1 (0.59) | ESR2ESR1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL123763 | 0.83 | ESR1 (0.59) | ESR2ESR1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL16191085 | 0.81 | CNR1 (0.42) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL10634189 | 0.81 | ESR1 (0.50) | ESR2ESR1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL1925358 | 0.79 | ESR1 (0.59) | ESR2ESR1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL23956535 | 0.78 | ESR1 (0.38) | ESR2ESR1ALDH1A1CYP3A4CNR1 | |
| SCHEMBL9757833 | 0.78 | ESR1 (0.53) | ESR2ESR1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL9247179 | 0.77 | ESR2 (0.56) | ESR2ESR1ALDH1A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459942-B1 | Inks | CIBA GEIGY AG (CH) | 1995-02-22 | — | — | EP | disclosed |
| US-5261953-A | CONTAINING WATER SOLUBLE STABILIZER TO IMPROVE COLORFASTNESS | CIBA-GEIGY CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| US-5089050-A | Phenol derivatives | CIBA-GEIGY CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0459942-A1 | Inks | CIBA-GEIGY AG (CH) | 1991-12-04 | — | — | EP | disclosed |