Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15625205 | 0.89 | ESR1 (0.52) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL8927410 | 0.89 | ESR1 (0.53) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL2287328 | 0.82 | ALDH1A1 (0.50) | ESR1ESR2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9351447 | 0.82 | LMNA (0.45) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL1129610 | 0.82 | ALDH1A1 (0.50) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL8367509 | 0.80 | ESR1 (0.41) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL13609961 | 0.79 | ESR1 (0.76) | ESR1ESR2ALDH1A1ALOX15HPGD | |
| SCHEMBL7761035 | 0.78 | ESR1 (0.56) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL9249100 | 0.78 | ESR2 (0.57) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL9757648 | 0.78 | ESR2 (0.57) | ESR1ESR2ALDH1A1CYP3A4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049685-A | Nuclear substituted salicylic acids and their salts | SANKO KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-09-17 | — | — | US | disclosed |