Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252917 | 0.80 | KCNN4 (0.38) | ALDH1A1TSHRTDP1CA2LMNA | |
| SCHEMBL11143059 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1CA2LMNA | |
| SCHEMBL11143057 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1CA2LMNA | |
| SCHEMBL1135764 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1CA2LMNA | |
| SCHEMBL11497885 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1CA2LMNA | |
| SCHEMBL9250883 | 0.73 | TRPA1 (0.42) | ALDH1A1TDP1CA2LMNASMN1; SMN2 | |
| SCHEMBL9244761 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRALOX15KDM4ESMN1; SMN2 | |
| SCHEMBL11355317 | 0.72 | ALDH1A1 (0.65) | ALDH1A1TSHRTDP1CA2LMNA | |
| SCHEMBL11516560 | 0.71 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1CA2LMNA | |
| SCHEMBL584830 | 0.71 | ALDH1A1 (0.71) | ALDH1A1TSHRTDP1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399284-B1 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0399284-A2 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |