Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.33 |
| ▸ | TERT | O14746 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713706 | 1.00 | GBA1 (0.35) | GBA1ALOX5TERTGMNNUSP2 | |
| SCHEMBL9249244 | 1.00 | GBA1 (0.35) | GBA1ALOX5TERTGMNNUSP2 | |
| SCHEMBL9249234 | 1.00 | GBA1 (0.35) | GBA1ALOX5TERTGMNNUSP2 | |
| SCHEMBL8715893 | 0.80 | FAAH (0.33) | ALOX5CYP1A2CYP2C19 | |
| SCHEMBL9247176 | 0.80 | FAAH (0.33) | ALOX5CYP1A2CYP2C19 | |
| SCHEMBL9247184 | 0.80 | FAAH (0.33) | ALOX5CYP1A2CYP2C19 | |
| SCHEMBL8715892 | 0.77 | FAAH (0.33) | ALOX5CYP1A2CYP2C19 | |
| SCHEMBL9244435 | 0.76 | TBXAS1 (0.40) | — | |
| SCHEMBL9246756 | 0.76 | TBXAS1 (0.40) | — | |
| SCHEMBL9244429 | 0.76 | TBXAS1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449785-A | Fungicides with triazole groups | HOFFMANN-LA ROCHE INC. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0524439-A1 | Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-01-27 | — | — | EP | disclosed |