Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Acetone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL6214608 | 1.00 | LMNA (0.75) | — | |
| Acetone SCHEMBL9592388 | 0.94 | — | — | |
| Acetone SCHEMBL9249276 | 0.94 | LMNA (0.86) | — | |
| Acetone SCHEMBL362166 | 0.94 | — | — | |
| Acetone SCHEMBL2726164 | 0.94 | — | — | |
| Acetone SCHEMBL3501755 | 0.94 | — | — | |
| Acetone SCHEMBL1653292 | 0.94 | — | — | |
| Acetone SCHEMBL98066 | 0.94 | — | — | |
| Acetone SCHEMBL7029361 | 0.94 | LMNA (0.86) | — | |
| Acetone SCHEMBL9248978 | 0.94 | LMNA (0.86) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103467479-B | Spiro-compound, its compositions, Preparation Method And The Use | 中国人民解放军军事医学科学院毒物药物研究所 | 2016-06-08 | — | — | CN | claimed |
| CN-103242348-B | Indoline diketopiperazine spiro-compound and preparation method and application thereof | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences PLA China (CN) | 2016-01-06 | — | — | CN | claimed |
| CN-103483410-B | Xanthoceraside preparation method | UNIV SHENYANG PHARMACEUTICAL | 2015-06-24 | — | — | CN | claimed |
| CN-103483410-A | Xanthoceraside preparation method | UNIV SHENYANG PHARMACEUTICAL | 2014-01-01 | — | — | CN | claimed |
| CN-103467479-A | Spiro compounds, compositions thereof, methods of making and uses thereof | INST PHARM & TOXICOLOGY AMMS | 2013-12-25 | — | — | CN | claimed |
| CN-103242348-A | Indoline diketopiperazine spiro-compound and preparation method and application thereof | INST PHARM & TOXICOLOGY AMMS | 2013-08-14 | — | — | CN | claimed |
| CN-102321130-A | Preparation method of picein | NANJING SORUN HERBAL TECH DEV | 2012-01-18 | — | — | CN | claimed |
| CN-102010457-A | Method for preparing raddeanin A | NANJING ZELANG AGRI DEV CO LTD | 2011-04-13 | — | — | CN | claimed |
| CN-101186620-B | Method for preparing phosphate of toluylene compounds containing phenol hydroxyl group | GUANGZHOU INST OF CHEMISTRY | 2010-09-08 | — | — | CN | claimed |
| CN-101186620-A | Method for preparing phosphate of toluylene compounds containing phenol hydroxyl group | GUANGZHOU INST OF CHEMISTRY (CN) | 2008-05-28 | — | — | CN | claimed |
| US-3976817-A | Method of preparing diffusion transfer image-receiving materials | FUJI PHOTO FILM CO., LTD. (JA) | 1976-08-24 | — | — | US | claimed |
| CN-117510552-A | Preparation of Fac-Ir (C≡N) 3 Method for photooxidation reduction of catalyst | 云南贵金属实验室有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-115433293-B | Preparation method of sodium gluconate | 苏州弘森药业股份有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-115650995-A | Preparation method of cefuroxime sodium | 浙江东盈药业有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115433293-A | Preparation method of sugammadex sodium | 苏州弘森药业股份有限公司 | 2022-12-06 | — | — | CN | disclosed |
| US-4252814-A | ANTIFERTILITY AGENTS, INSECTICIDES | AMERICAN CYANAMID COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| US-4202891-A | ANOREXIGENIC AGENTS, ANTICHOLESTEROL AGENTS, INHIBITORS OF CELL GROWTH | PARISH, EDWARD J. | 1980-05-13 | — | — | US | disclosed |
| US-4085000-A | TERPOLYMER OF ALLYL ALCOHOL, ALPHA-BETA-UNSATURATED ACID, AND ALKYLATE OF A ALPHA-BETA-UNSATURATED ACID | BASF WYANDOTTE CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-4046909-A | Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-09-06 | — | — | US | disclosed |
| US-3998958-A | Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-12-21 | — | — | US | disclosed |