Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244519 | 0.91 | GAA (0.38) | GAARENKDM4EALDH1A1MAPT | |
| SCHEMBL9244509 | 0.91 | GAA (0.38) | GAARENKDM4EALDH1A1MAPT | |
| SCHEMBL9567750 | 0.86 | GAA (0.38) | GAARENSLC18A2KDM4EALDH1A1 | |
| SCHEMBL9249046 | 0.84 | REN (0.43) | GAARENHSD17B10 | |
| SCHEMBL9244403 | 0.84 | POLB (0.45) | KCNA5SCN5ASLC18A2 | |
| SCHEMBL9245399 | 0.83 | REN (0.34) | GAARENHSD17B10 | |
| SCHEMBL9250617 | 0.81 | KCNA5 (0.43) | KCNA5SCN5ASLC18A2 | |
| SCHEMBL9250615 | 0.78 | REN (0.34) | REN | |
| SCHEMBL9250622 | 0.78 | REN (0.34) | REN | |
| SCHEMBL9249050 | 0.78 | KCNA5 (0.39) | KCNA5SCN5ASLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449785-A | Fungicides with triazole groups | HOFFMANN-LA ROCHE INC. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0524439-A1 | Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-01-27 | — | — | EP | disclosed |