Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946547 | 0.91 | TSHR (0.53) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL380050 | 0.86 | ALDH1A1 (0.76) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL27811431 | 0.84 | ALDH1A1 (0.73) | ALDH1A1TSHRGLAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3454478 | 0.84 | ALDH1A1 (0.73) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL9249496 | 0.83 | TSHR (0.53) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL11318625 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL11438699 | 0.82 | TSHR (0.44) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL11431871 | 0.82 | TSHR (0.44) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL4207496 | 0.81 | TSHR (0.51) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL2577552 | 0.81 | TSHR (0.54) | ALDH1A1TSHRGLAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410900-B1 | Method for the preparation of methylene di(phenylurethane) | RHONE POULENC CHIMIE (FR) | 1995-03-15 | — | — | EP | claimed |