Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6417722 | 0.79 | CYP2D6 (0.40) | CYP2D6LMNAHPGDCYP17A1MC4R | |
| SCHEMBL8516718 | 0.79 | CYP2D6 (0.40) | CYP2D6LMNAHPGDCYP17A1MC4R | |
| SCHEMBL6417725 | 0.79 | CYP2D6 (0.40) | CYP2D6LMNAHPGDCYP17A1MC4R | |
| Hydrochloric Acid SCHEMBL8150974 | 0.77 | CYP17A1 (0.40) | CYP2D6LMNAHPGDCYP17A1MC4R | |
| Hydrochloric Acid SCHEMBL8143807 | 0.77 | CYP17A1 (0.40) | CYP2D6LMNAHPGDCYP17A1MC4R | |
| SCHEMBL5961280 | 0.75 | TRPA1 (0.42) | LMNATHRBHPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL22639047 | 0.75 | LMNA (0.44) | LMNATHRBHPGDL3MBTL1KDM4E | |
| SCHEMBL30745623 | 0.74 | CYP17A1 (0.37) | CYP2D6LMNACYP17A1MC4RCYP26A1 | |
| SCHEMBL12770874 | 0.73 | CYP2D6 (0.54) | CYP2D6LMNAHPGDCYP17A1MC4R | |
| SCHEMBL12770872 | 0.73 | CYP2D6 (0.54) | CYP2D6LMNAHPGDCYP17A1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8411347-B2 | Composition comprising photochromic dyes in an ionic solvent | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2013-04-02 | — | — | US | disclosed |
| US-20110013252-A1 | COMPOSITION COMPRISING PHOTOCHROMIC DYES IN AN IONIC SOLVENT | Essilor International (compagnie Generale D'optiqu e (FR) | 2011-01-20 | — | — | US | disclosed |