Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256722 | 0.91 | CYP2D6 (0.48) | ESR1SLC6A2SLC6A3ADRA2ACYP2D6 | |
| SCHEMBL9252381 | 0.80 | IDO1 (0.41) | SLC6A2SLC6A3ADRA2ACYP2D6CHRM2 | |
| SCHEMBL9253956 | 0.80 | IDO1 (0.40) | SLC6A2SLC6A3ADRA2ACYP2D6CHRM2 | |
| SCHEMBL8643817 | 0.75 | DRD3 (0.59) | SLC6A2SLC6A3ADRA2ACYP2D6CHRM2 | |
| SCHEMBL9256723 | 0.74 | DRD3 (0.54) | SLC6A2SLC6A3ADRA2ACYP2D6CHRM2 | |
| SCHEMBL9256621 | 0.74 | IDO1 (0.51) | SLC6A2SLC6A3ADRA2ACYP2D6CHRM2 | |
| SCHEMBL9256092 | 0.74 | SLC6A2 (0.40) | ESR1SLC6A2SLC6A3ADRA2AOPRM1 | |
| SCHEMBL9250050 | 0.72 | SLC6A3 (0.44) | SLC6A2SLC6A3ADRA2ACYP2D6CHRM2 | |
| SCHEMBL9257208 | 0.72 | IDO1 (0.51) | SLC6A2SLC6A3ADRA2ACYP2D6CHRM2 | |
| SCHEMBL9250340 | 0.72 | IDO1 (0.50) | SLC6A2SLC6A3ADRA2ACYP2D6CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |