Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668868 | 0.90 | ACP3 (0.38) | SLC6A2SLC6A4SLC6A3ADRA2AADRA2B | |
| SCHEMBL9257877 | 0.79 | CA1 (0.40) | SLC6A2SLC6A4SLC6A3ADRA2AADRA2B | |
| SCHEMBL9257472 | 0.78 | MCOLN2 (0.36) | IDO1TDO2ALDH1A1 | |
| SCHEMBL9253636 | 0.78 | OPRL1 (0.38) | SLC6A2SLC6A4SLC6A3ADRA2AOPRM1 | |
| SCHEMBL9250047 | 0.74 | ESR1 (0.48) | SLC6A2SLC6A4SLC6A3ADRA2AADRA2B | |
| SCHEMBL4674804 | 0.72 | IDO1 (0.39) | OPRD1GAAIDO1 | |
| SCHEMBL9668878 | 0.71 | OPRD1 (0.40) | OPRM1OPRD1OPRK1OPRL1GAA | |
| SCHEMBL9251008 | 0.70 | IDO1 (0.43) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| SCHEMBL9256722 | 0.69 | CYP2D6 (0.48) | SLC6A2SLC6A4SLC6A3ADRA2AADRA2B | |
| SCHEMBL9256103 | 0.69 | CHRNA7 (0.34) | OPRM1OPRD1OPRK1OPRL1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |