Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.46 |
| ▸ | PDE2A | O00408 | 5/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3151764 | 0.85 | EPHX2 (0.36) | EPHX2PDE2AGRM2 | |
| SCHEMBL929959 | 0.77 | RAB9A (0.46) | — | |
| SCHEMBL30883901 | 0.77 | RAB9A (0.46) | — | |
| SCHEMBL425877 | 0.75 | EPHX2 (0.50) | EPHX2PDE2ASLC7A5 | |
| SCHEMBL29855116 | 0.75 | EPHX2 (0.50) | EPHX2PDE2ASLC7A5 | |
| SCHEMBL9013336 | 0.75 | — | — | |
| SCHEMBL12566385 | 0.74 | EPHX2 (0.53) | EPHX2PDE2ASLC7A5 | |
| SCHEMBL6142235 | 0.73 | CA12 (0.31) | — | |
| SCHEMBL2093568 | 0.72 | EPHX2 (0.51) | EPHX2PDE2ASLC7A5FAAHCTSK | |
| SCHEMBL1253983 | 0.71 | EPHX2 (0.54) | EPHX2PDE2ASLC7A5FAAHCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881664-A | Cycloalkyl 3-oxopiperazine carboxamides and cycloheteroalkyl 3-oxopiperazine carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2024-04-12 | — | — | CN | disclosed |
| US-5468421-A | Cyclohexane derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1995-11-21 | — | — | US | disclosed |