Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.31 |
| ▸ | CA1 | P00915 | 4/20 | 0.31 |
| ▸ | CA9 | Q16790 | 4/20 | 0.31 |
| ▸ | APLNR | P35414 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856992 | 0.80 | TRPA1 (0.41) | ALOX5APFEN1 | |
| SCHEMBL19321885 | 0.78 | ACHE (0.35) | CA12CA1CA9APLNRDRD2 | |
| SCHEMBL29425597 | 0.78 | APLNR (0.47) | APLNR | |
| SCHEMBL23190575 | 0.78 | CA12 (0.46) | CA12CA1CA9APLNRDRD2 | |
| SCHEMBL2412558 | 0.78 | APLNR (0.47) | APLNR | |
| SCHEMBL7757991 | 0.78 | ALOX5AP (0.35) | CA12CA1CA9APLNRALOX5AP | |
| SCHEMBL4978091 | 0.77 | SLC6A4 (0.39) | — | |
| SCHEMBL19354829 | 0.77 | SLC6A4 (0.36) | CA12CA1CA9APLNRDRD2 | |
| SCHEMBL18359614 | 0.77 | ALOX5AP (0.37) | CA12CA1CA9APLNRDRD2 | |
| SCHEMBL19317227 | 0.77 | ALOX5AP (0.38) | CA12CA1CA9APLNRALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1493741-A2 | Benzo[b]thiophene compounds, intermediates, processes, compositions and methods | Eli Lilly & Company (US) | 2005-01-05 | — | — | EP | disclosed |
| EP-0826683-B1 | Benzo[B]thiophene compounds, intermediates, processes, compositions, and methods | LILLY CO ELI (US) | 2004-10-06 | — | — | EP | disclosed |
| US-5998442-A | ANTICHOLESTEROL AGENTS | ELI LILLY AND COMPANY (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0826683-A1 | Benzo[B]thiophene compounds, intermediates, processes, compositions, and methods | ELI LILLY AND COMPANY (US) | 1998-03-04 | — | — | EP | disclosed |