Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | USP5 | P45974 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850888 | 0.99 | HTR2A (0.37) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL2850582 | 0.92 | CCR2 (0.35) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL9349604 | 0.92 | USP5 (0.35) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL9349590 | 0.92 | USP5 (0.35) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL9979962 | 0.92 | USP5 (0.35) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL9250171 | 0.92 | USP5 (0.35) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL9349609 | 0.92 | USP5 (0.35) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL2850477 | 0.90 | KDM1A (0.32) | HTR2AHTR2CHTR2BCCR2KDM1A | |
| SCHEMBL2850922 | 0.88 | KDM1A (0.33) | HTR2AHTR2CHTR2BCCR2KDM1A | |
| SCHEMBL2845403 | 0.87 | HTR2A (0.37) | HTR2AHTR2CHTR2BUSP5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100264368-A1 | LIQUID CRYSTAL MOLECULES COMPRISING HYDROAZULENE STRUCTURES | TETRAGON-CHEMIE AG (LI) | 2010-10-21 | — | — | US | disclosed |
| EP-1896552-B1 | LIQUID CRYSTAL MOLECULES COMPRISING HYDROAZULENE STRUCTURES | TETRAGON CHEMIE AG (LI) | 2010-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100264368-A1 | LIQUID CRYSTAL MOLECULES COMPRISING HYDROAZULENE STRUCTURES | FLI1, F12, GTF2I | HTR2A 1591/4885HTR2C 661/4885HTR2B 2270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.