Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6379829 | 0.86 | NPC1 (0.55) | NPC1RAB9ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL23681183 | 0.84 | NPC1 (0.54) | NPC1RAB9ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL11302875 | 0.81 | NPC1 (0.51) | NPC1RAB9ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL1531737 | 0.80 | MAPT (0.50) | NPC1RAB9ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL1433300 | 0.79 | NPC1 (0.60) | NPC1RAB9ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL422787 | 0.78 | RAB9A (0.62) | NPC1RAB9ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL7757826 | 0.78 | NPC1 (0.58) | NPC1RAB9ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL6830087 | 0.78 | NPC1 (0.58) | NPC1RAB9ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL10390082 | 0.77 | NPC1 (0.51) | NPC1HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL27487815 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379003-B1 | Thiophene-2-carboxylic-acid derivatives, process for their preparation and their use in combating undesired plant growth | BASF AG (DE) | 1995-01-25 | — | — | EP | claimed |
| US-5034049-A | Plant growth regulators, esters or oxyamides of thiophene | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-23 | — | — | US | disclosed |
| US-4920110-A | PESTICIDES, MITICIDES, TICKS, NEMATOCIDES | BASF AKTIENGESELLSCHAFT (DE) | 1990-04-24 | — | — | US | disclosed |
| EP-0258790-A2 | Furan- or thiophenecarboxylic-acid propargyl esters | BASF Aktiengesellschaft (DE) | 1988-03-09 | — | — | EP | disclosed |
| EP-0258790-A2 | Furan- or thiophenecarboxylic-acid propargyl esters | BASF Aktiengesellschaft (DE) | 1988-03-09 | — | — | EP | disclosed |