Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250248 | 1.00 | AHR (0.61) | AHRKDM4ENPC1RAB9ADHFR | |
| SCHEMBL9682732 | 0.81 | RAB9A (0.51) | AHRKDM4ENPC1RAB9ADHFR | |
| SCHEMBL9682730 | 0.81 | RAB9A (0.51) | AHRKDM4ENPC1RAB9ADHFR | |
| SCHEMBL10580737 | 0.78 | KMT2A (0.61) | KDM4ENPC1RAB9AALOX5PTGS1 | |
| SCHEMBL10580735 | 0.78 | KMT2A (0.61) | KDM4ENPC1RAB9AALOX5PTGS1 | |
| SCHEMBL9679426 | 0.78 | AHR (0.74) | AHRKDM4ENPC1RAB9AALOX5 | |
| SCHEMBL20582895 | 0.78 | AHR (0.74) | AHRKDM4ENPC1RAB9AALOX5 | |
| SCHEMBL699666 | 0.78 | AHR (0.74) | AHRKDM4ENPC1RAB9AALOX5 | |
| SCHEMBL260347 | 0.78 | AHR (0.74) | AHRKDM4ENPC1RAB9AALOX5 | |
| SCHEMBL9679429 | 0.78 | AHR (0.74) | AHRKDM4ENPC1RAB9AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7285937-A | — | — | None | — | — | JP | disclosed |
| JP-H07285937-A | PYRIDINE DERIVATIVE AND PRODUCTION THEREOF | NIPPON IYAKUHIN KAIHATSU KENKYUSHO:KK | 1995-10-31 | — | — | JP | disclosed |