Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246804 | 0.88 | MAOA (0.66) | TTRMAOACA12CA9MAPT | |
| SCHEMBL21467878 | 0.87 | TTR (0.58) | TTRCA1CA2CA12CA9 | |
| SCHEMBL9252118 | 0.83 | MAOA (0.67) | TTRMAOACA12CA9MAPT | |
| SCHEMBL21468177 | 0.81 | TTR (0.62) | TTRMAOACA1CA2CA12 | |
| SCHEMBL11728871 | 0.79 | TTR (0.71) | TTRMAOACA1CA2MAPT | |
| SCHEMBL29465920 | 0.79 | TTR (0.71) | TTRMAOACA1CA2MAPT | |
| SCHEMBL25625936 | 0.79 | MAOA (0.58) | TTRMAOACA1CA2CA12 | |
| SCHEMBL31423805 | 0.76 | MAOA (0.77) | MAOAMAPTTP53KDM4EMEN1 | |
| SCHEMBL7337235 | 0.76 | MAOA (0.77) | MAOAMAPTTP53KDM4EMEN1 | |
| SCHEMBL21467879 | 0.76 | TTR (0.58) | TTRCA1CA2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395881-A | PVC-free, chlorine-free blends; a non-polar thermoplastic polyolefin, a polar ethylene copolymer, an epoxy functionalized polar ethylene copolymer, and a carboxylic acid or anhydride functionalized olefin polymer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-03-07 | — | — | US | disclosed |
| US-5395914-A | Nucleophilic polycondensation of hydroxy halogen xanthones | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0571883-A1 | Polyarylethers with xanthone units, method for their production and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-01 | — | — | EP | disclosed |