Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.66 |
| ▸ | TTR | P02766 | 3/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | FASN | P49327 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252118 | 0.92 | MAOA (0.67) | MAOATTRESR2ESR1AHR | |
| SCHEMBL31423805 | 0.88 | MAOA (0.77) | MAOAESR2ESR1MGAMFASN | |
| SCHEMBL7337235 | 0.88 | MAOA (0.77) | MAOAESR2ESR1MGAMFASN | |
| SCHEMBL9250307 | 0.88 | TTR (0.57) | MAOATTRESR2AHRKDM4E | |
| SCHEMBL2768245 | 0.86 | AHR (0.61) | MAOATTRESR2ESR1AHR | |
| SCHEMBL11728871 | 0.84 | TTR (0.71) | MAOATTRAHRKDM4EMAPT | |
| Euxanthone SCHEMBL2161295 | 0.84 | MAOA (0.81) | MAOAESR2ESR1MGAMFASN | |
| SCHEMBL29465920 | 0.84 | TTR (0.71) | MAOATTRAHRKDM4EMAPT | |
| SCHEMBL10913158 | 0.81 | KDM4E (0.75) | MAOATTRAHRKDM4EMAPT | |
| SCHEMBL24343643 | 0.81 | AHR (0.62) | MAOATTRESR2ESR1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2842937-B1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-9657043-B2 | Amine compound and use thereof for medical purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9657043-B2 | Amine compound and use thereof for medical purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9657043-B2 | Amine compound and use thereof for medical purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| EP-2842937-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-03-04 | — | — | EP | disclosed |
| US-5395914-A | Nucleophilic polycondensation of hydroxy halogen xanthones | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0571883-A1 | Polyarylethers with xanthone units, method for their production and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-01 | — | — | EP | disclosed |
| US-4954604-A | High molecular weight, crystalline | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | HLA-B, HLA-A, HLA-C | MAOA 131/4885TTR 2178/4885ESR2 2804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.