Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247853 | 0.92 | LMNA (0.55) | HPGDLMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL2549970 | 0.81 | LMNA (0.60) | HPGDLMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL4627854 | 0.81 | ALDH1A1 (0.61) | HPGDLMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL19795501 | 0.80 | ALDH1A1 (0.56) | HPGDLMNAMAPTSMN1; SMN2TSHR | |
| SCHEMBL9248670 | 0.79 | CYP1A2 (0.60) | HPGDLMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL9247954 | 0.78 | HPGD (0.56) | HPGDLMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL21866043 | 0.77 | ALDH1A1 (0.57) | HPGDMAPTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL827863 | 0.77 | TSHR (0.70) | LMNAMAPTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL9244541 | 0.76 | CYP1A2 (0.65) | HPGDLMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL1110997 | 0.75 | GAA (0.57) | HPGDLMNAMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355774-B1 | Nucleus-fluorinated aromatic carboxylates and processes for their production | ASAHI GLASS CO LTD (JP) | 1995-04-26 | — | — | EP | disclosed |
| US-4985588-A | Nucleus-fluorinated aromatic carboxylates and processes for their production | ASAHI GLASS COMPANY LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0355774-A2 | Nucleus-fluorinated aromatic carboxylates and processes for their production | ASAHI GLASS COMPANY LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |