Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPR3 | P17342 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292700 | 0.91 | AAK1 (0.45) | KMT2ALMNASLC7A5AAK1ALDH1A1 | |
| SCHEMBL16061270 | 0.91 | CA1 (0.43) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL16060815 | 0.87 | NR1H4 (0.41) | LMNASLC7A5CA2ALDH1A1HTT | |
| SCHEMBL3827736 | 0.80 | SLC6A2 (0.51) | KMT2ASLC7A5MEN1MAPTALDH1A1 | |
| SCHEMBL6822603 | 0.80 | DGAT1 (0.36) | KMT2ALMNASLC7A5CA12CA1 | |
| SCHEMBL2952178 | 0.80 | DGAT1 (0.36) | KMT2ALMNASLC7A5CA12CA1 | |
| SCHEMBL16061410 | 0.79 | NR1H4 (0.38) | LMNASLC7A5MAPTSMN1; SMN2 | |
| SCHEMBL8489202 | 0.77 | GSK3B (0.52) | SLC7A5TRPA1 | |
| SCHEMBL3829355 | 0.76 | CYP1A2 (0.45) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL8489216 | 0.74 | LMNA (0.42) | LMNAAAK1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453464-A | Bis-acetoacetates and bis-beta-ketoesters, crosslinkers for hydroxy containing polymers, films | EASTMAN CHEMICAL COMPANY (US) | 1995-09-26 | — | — | US | disclosed |