Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16033393 | 0.86 | EGLN1 (0.46) | CYP1A2ALDH1A1KDM6BKDM5CEGLN1 | |
| SCHEMBL36130 | 0.82 | TP53 (0.42) | CYP1A2TSHRFFAR3GABRPGABRD | |
| SCHEMBL27881916 | 0.79 | TP53 (0.40) | CYP1A2FFAR3TP53 | |
| SCHEMBL5799807 | 0.79 | EGLN1 (0.45) | CYP1A2ALDH1A1KDM6BKDM5CEGLN1 | |
| SCHEMBL7621862 | 0.77 | KDM2A (0.43) | CYP1A2ALDH1A1KDM6BKDM5CEGLN1 | |
| SCHEMBL5799804 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL16540946 | 0.76 | GABRP (0.45) | CYP1A2ALDH1A1KDM6BKDM5CEGLN1 | |
| SCHEMBL935214 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53ADRA2AADRA1A | |
| SCHEMBL9419623 | 0.75 | TP53 (0.36) | CYP1A2TSHRFFAR3TP53 | |
| SCHEMBL17654220 | 0.75 | TP53 (0.36) | CYP1A2ALDH1A1TSHRFFAR3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457055-A | Determining methylmalonic acid concenration in spinal fluid by gas chromatography | THE UNIVERSITY OF COLORADO FOUNDATION (US) | 1995-10-10 | — | — | US | disclosed |