SCHEMBL9250665

SCHEMBL9250665

CN(C)Cc1cc(CN(C)C)c(O)c(CN(C)C)c1.[LiH]

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.77
ALOX15 P16050 2/20 0.77
CYP2C9 P11712 1/20 0.77
CYP2C19 P33261 1/20 0.59
MAPK1 P28482 1/20 0.59
HTT P42858 1/20 0.59
ALDH1A1 P00352 6/20 0.57
GAA P10253 3/20 0.54
KDM4E B2RXH2 3/20 0.54
MAPT P10636 2/20 0.54
MEN1 O00255 1/20 0.54
POLB P06746 1/20 0.54
THRB P10828 1/20 0.54
G6PD P11413 1/20 0.54
PABPC1 P11940 1/20 0.54
KMT2A Q03164 1/20 0.54
HKDC1 Q2TB90 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
TSHR P16473 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28273434 0.98 HSD17B10 (0.80) HSD17B10ALOX15CYP2C9CYP2C19MAPK1
SCHEMBL36297 0.98 HSD17B10 (0.80) HSD17B10ALOX15CYP2C9CYP2C19MAPK1
SCHEMBL25305838 0.95 HSD17B10 (0.77) HSD17B10ALOX15CYP2C9CYP2C19MAPK1
Ammonia Solution, Strong SCHEMBL4827174 0.95 HSD17B10 (0.77) HSD17B10ALOX15CYP2C9CYP2C19MAPK1
SCHEMBL25306052 0.95 HSD17B10 (0.77) HSD17B10ALOX15CYP2C9CYP2C19MAPK1
Dimethylamine SCHEMBL28105045 0.91 HSD17B10 (0.71) HSD17B10ALOX15CYP2C9CYP2C19MAPK1
SCHEMBL13038516 0.87 HSD17B10 (1.00) HSD17B10ALOX15CYP2C9CYP2C19MAPK1
SCHEMBL11406770 0.86 HSD17B10 (0.64) HSD17B10ALOX15CYP2C9CYP2C19MAPK1
Thiocyanic Acid SCHEMBL5827196 0.86 HSD17B10 (0.65) HSD17B10ALOX15CYP2C9CYP2C19MAPK1
SCHEMBL2879776 0.86 ALOX15 (0.65) HSD17B10ALOX15CYP2C9CYP2C19MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4204474-A1 THERMALLY CURABLE COMPOSITIONS, THERMALLY CURED COMPOSITIONS, AND ARTICLES PREPARED THEREFROM 3M Innovative Properties Company (US) 2023-07-05 EP claimed
US-12545782-B2 Thermally curable compositions, thermally cured compositions, and articles prepared therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-02-10 US disclosed
US-20230279216-A1 THERMALLY CURABLE COMPOSITIONS, THERMALLY CURED COMPOSITIONS, AND ARTICLES PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2023-09-07 US disclosed
EP-4204474-A1 THERMALLY CURABLE COMPOSITIONS, THERMALLY CURED COMPOSITIONS, AND ARTICLES PREPARED THEREFROM 3M Innovative Properties Company (US) 2023-07-05 EP disclosed
US-5470896-A Storage-stable solutions of accelerator systems CIBA-GEIGY CORPORATION (US) 1995-11-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545782-B2 Thermally curable compositions, thermally cured compositions, and articles prepared therefrom TERT, ARCN1, MRPL12 HSD17B10 4167/4885ALOX15 1067/4885CYP2C9 4753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.