Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253983 | 0.98 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL9246829 | 0.98 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL9246736 | 0.89 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL11593239 | 0.85 | SIGMAR1 (0.50) | ALDH1A1SMN1; SMN2SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL12881355 | 0.84 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL12772769 | 0.83 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL9281457 | 0.82 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL11023837 | 0.82 | SIGMAR1 (0.51) | ALDH1A1SIGMAR1CYP1A2CYP2D6TSHR | |
| SCHEMBL12014416 | 0.82 | SIGMAR1 (0.48) | ALDH1A1SIGMAR1CYP1A2CYP2D6TSHR | |
| SCHEMBL167209 | 0.80 | KMT2A (0.51) | ALDH1A1SMN1; SMN2SIGMAR1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527427-B1 | Catalysts and casting article, method, and composition | MINNESOTA MINING & MFG (US) | 1995-11-15 | — | — | EP | disclosed |
| US-5244997-A | Polyurethane | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0527427-A2 | Catalysts and casting article, method, and composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-02-17 | — | — | EP | disclosed |