SCHEMBL9250688

SCHEMBL9250688

Cc1cc(OS(C)(=O)=O)n[nH]1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.39
DAO P14920 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.34
ALK Q9UM73 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 1/20 0.32
LMNA P02545 1/20 0.31
GRM5 P41594 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31
CCNA1 P78396 1/20 0.31
PDE10A Q9Y233 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3261591 0.73
SCHEMBL11545262 0.72 KDM4E (0.43) NPC1RAB9ALMNAKDM4E
SCHEMBL7759319 0.71
SCHEMBL12744427 0.71 CYP2C9 (0.33) HCAR2DAOSMN1; SMN2
SCHEMBL27382966 0.71
SCHEMBL21436736 0.68 HCAR1 (0.33) GRM5
SCHEMBL3261563 0.68 BTK (0.41) HCAR2DAOL3MBTL1SMN1; SMN2NPC1
SCHEMBL2725056 0.68
SCHEMBL3261615 0.68 CYP2C9 (0.38) HCAR2DAOL3MBTL1SMN1; SMN2LMNA
SCHEMBL3264081 0.67 CYP2C9 (0.37) HCAR2DAOL3MBTL1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0636121-A1 ARTHROPODICIDAL PYRAZOLE SULFONATES Dunlena Pty. Limited (AU) 1995-02-01 EP disclosed
WO-1993021160-A1 ARTHROPODICIDAL PYRAZOLE SULFONATES DUNLENA PTY. LTD. (AU) 1993-10-28 WO disclosed