SCHEMBL11545262

SCHEMBL11545262

CS(=O)(=O)Oc1ccc(=O)[nH]n1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
AKR1B1 P15121 8/20 0.41
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 3/20 0.39
MEN1 O00255 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21436736 0.74 HCAR1 (0.33) ALDH1A1
SCHEMBL9250688 0.72 HCAR2 (0.39) KDM4ENPC1RAB9ALMNA
SCHEMBL29277131 0.72 HCAR1 (0.32)
SCHEMBL7805216 0.72 KDM4E (0.45) KDM4ENPC1RAB9AAKR1B1ALDH1A1
SCHEMBL11710435 0.71 LMNA (0.61) KDM4ENPC1RAB9AALDH1A1KMT2A
SCHEMBL11708574 0.70 LMNA (0.47) KDM4ENPC1RAB9AALDH1A1KMT2A
SCHEMBL14715589 0.67 ALDH1A1 (0.49) KDM4ENPC1RAB9AALDH1A1KMT2A
Water SCHEMBL16192665 0.65 ALDH1A1 (0.44) KDM4ENPC1RAB9AAKR1B1ALDH1A1
SCHEMBL1009470 0.65 CYP1A2 (0.48) KDM4ENPC1RAB9AAKR1B1ALDH1A1
SCHEMBL11427461 0.65 KDM4E (0.49) KDM4ENPC1RAB9AAKR1B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4140768-A INSECTICIDES, FUNGICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-02-20 US disclosed