Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249824 | 0.85 | SETD7 (0.57) | OPRM1OPRD1OPRK1P2RX7SIGMAR1 | |
| SCHEMBL9253664 | 0.82 | HTR1A (0.49) | P2RX7DRD2DRD3GLA | |
| SCHEMBL9252997 | 0.81 | SETD7 (0.56) | OPRM1OPRD1OPRK1P2RX7SIGMAR1 | |
| SCHEMBL11548124 | 0.81 | KMT2A (0.55) | OPRM1OPRD1OPRK1P2RX7CYP2D6 | |
| SCHEMBL9253052 | 0.80 | SETD7 (0.54) | OPRM1OPRD1OPRK1P2RX7SIGMAR1 | |
| SCHEMBL9256632 | 0.80 | SETD7 (0.54) | OPRM1OPRD1OPRK1P2RX7SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11541436 | 0.80 | KMT2A (0.54) | OPRM1OPRD1OPRK1P2RX7CYP2D6 | |
| SCHEMBL9053981 | 0.78 | KDM4E (0.42) | OPRM1OPRD1OPRK1P2RX7SIGMAR1 | |
| SCHEMBL11545203 | 0.78 | KMT2A (0.65) | OPRM1OPRD1OPRK1CYP2D6SETD7 | |
| SCHEMBL9246640 | 0.76 | SETD7 (0.61) | OPRM1OPRD1OPRK1P2RX7SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| CN-1058780-A | Has the active thiazolidine carboxylic acid amides derivative of anti-allergy, their preparation and application | SANKYO CO (JP) | 1992-02-19 | — | — | CN | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |