Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256632 | 1.00 | SETD7 (0.54) | SETD7OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL9252997 | 0.98 | SETD7 (0.56) | SETD7OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL9249824 | 0.94 | SETD7 (0.57) | SETD7OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL9246640 | 0.87 | SETD7 (0.61) | SETD7OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL13904314 | 0.82 | SIGMAR1 (0.59) | SETD7OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL9253379 | 0.81 | SETD7 (0.57) | SETD7OPRM1OPRD1OPRK1P2RX7 | |
| SCHEMBL9250439 | 0.81 | OPRD1 (0.50) | SETD7OPRM1OPRD1OPRK1P2RX7 | |
| SCHEMBL9250848 | 0.80 | OPRM1 (0.44) | SETD7OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL9253928 | 0.79 | SETD7 (0.51) | SETD7OPRM1OPRD1OPRK1P2RX7 | |
| SCHEMBL9235468 | 0.79 | SETD7 (0.62) | SETD7OPRM1OPRD1OPRK1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |