Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97872 | 0.71 | KEAP1 (0.48) | KEAP1CA12CA1CA2CA9 | |
| SCHEMBL9449848 | 0.68 | PTGS1 (0.38) | — | |
| SCHEMBL4679904 | 0.67 | — | — | |
| SCHEMBL195978 | 0.67 | KIF11 (0.42) | KEAP1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL2206669 | 0.67 | EP300 (0.46) | KEAP1CA12CA1CA2CA9 | |
| SCHEMBL2292289 | 0.67 | MAP2K4 (0.38) | KEAP1CA12CA1CA2CA9 | |
| SCHEMBL2207059 | 0.67 | EP300 (0.46) | KEAP1CA12CA1CA2CA9 | |
| SCHEMBL5158336 | 0.67 | SMN1; SMN2 (0.34) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL183564 | 0.65 | KEAP1 (0.57) | KEAP1CA12CA1CA2CA9 | |
| SCHEMBL2207940 | 0.65 | KEAP1 (0.48) | KEAP1ALDH1A1HTTEP300KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0215124-B1 | SILVER HALIDE PHOTOGRAPHIC PHOTO-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-04 | — | — | EP | disclosed |
| US-4925782-A | Silver halide photographic light-sensitive element containing water soluble dye compounds | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0215124-A1 | SILVER HALIDE PHOTOGRAPHIC PHOTO-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |