Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9243360 | 0.86 | GABRA1 (0.54) | GABRA1GABRB2ELANECTSG | |
| SCHEMBL166573 | 0.82 | GABRA1 (0.41) | GABRA1GABRB2ESR1 | |
| SCHEMBL29619533 | 0.82 | GABRA1 (0.41) | GABRA1GABRB2ESR1 | |
| SCHEMBL248342 | 0.79 | GABRA1 (0.48) | GABRA1GABRB2ELANECTSGPTGS1 | |
| Ammonia Solution, Strong SCHEMBL27539208 | 0.79 | GABRA1 (0.39) | GABRA1GABRB2 | |
| Ethylene SCHEMBL27502363 | 0.76 | GABRA1 (0.38) | GABRA1GABRB2 | |
| SCHEMBL9064419 | 0.74 | GABRA1 (0.40) | GABRA1GABRB2PTGS1LMNATSHR | |
| SCHEMBL11207425 | 0.74 | TDP1 (0.43) | GABRA1GABRB2LMNACYP2C9HTR2A | |
| SCHEMBL6711531 | 0.74 | GABRA1 (0.36) | GABRA1GABRB2 | |
| SCHEMBL4960855 | 0.73 | GABRA1 (0.54) | GABRA1GABRB2ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436402-A | Reaction of o- or p-isobutylethylbenzene in the presence of a disproportionation acid catalyst and sec-butylethylbenzenne | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0347939-B1 | METHOD FOR PREPARING ALPHA-(4-ISOBUTYLPHENYL) PROPIONIC ACID OR ITS PRECURSOR | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1993-08-25 | — | — | EP | disclosed |
| EP-0373362-B1 | METHOD FOR PREPARING P-ISOBUTYLSTYRENE | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1993-02-03 | — | — | EP | disclosed |
| US-5097061-A | From isobutylbenzene and ethylene, dehydrogenation, carboxylation of the p-isobutylstyrene product, catalytic | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1992-03-17 | — | — | US | disclosed |
| EP-0373362-A1 | Method for preparing p-isobutylstyrene | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-06-20 | — | — | EP | disclosed |
| EP-0347939-A1 | Method for preparing alpha-(4-isobutylphenyl) propionic acid or its precursor | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |