Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | HAO1 | Q9UJM8 | 3/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.45 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981349 | 0.94 | GSK3B (0.63) | GSK3BMMP2CA1CA2RAB9A | |
| Ethylene SCHEMBL8830351 | 0.91 | GSK3B (0.59) | GSK3BMMP2CA1CA2RAB9A | |
| SCHEMBL17857765 | 0.91 | GSK3B (0.63) | GSK3BMMP2CA1CA2MMP13 | |
| SCHEMBL6829508 | 0.86 | GSK3B (0.58) | GSK3BMMP2CA1CA2RAB9A | |
| SCHEMBL11983785 | 0.85 | GSK3B (0.70) | GSK3BCA1CA2RAB9ASMN1; SMN2 | |
| SCHEMBL7862874 | 0.84 | SMN1; SMN2 (0.66) | GSK3BMMP2CA1CA2MMP13 | |
| SCHEMBL17973377 | 0.84 | GSK3B (0.56) | GSK3BMMP2CA1CA2MMP13 | |
| SCHEMBL28043310 | 0.81 | KMT2A (0.65) | GSK3BCA1CA2ERCC5FEN1 | |
| SCHEMBL6291931 | 0.80 | GSK3B (0.89) | GSK3BMMP2CA1CA2MMP3 | |
| SCHEMBL8532726 | 0.79 | ERCC5 (0.71) | GSK3BHAO1ERCC5FEN1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |