Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981349 | 0.91 | GSK3B (0.63) | GSK3BCA1CA2POLBRAB9A | |
| Ethylene SCHEMBL8830351 | 0.87 | GSK3B (0.59) | GSK3BCA1CA2POLBRAB9A | |
| SCHEMBL9251049 | 0.86 | GSK3B (0.58) | GSK3BCA1CA2POLBRAB9A | |
| SCHEMBL11983785 | 0.85 | GSK3B (0.70) | GSK3BCA1CA2POLBRAB9A | |
| SCHEMBL28043310 | 0.81 | KMT2A (0.65) | GSK3BCA1CA2POLBRAB9A | |
| SCHEMBL17857765 | 0.79 | GSK3B (0.63) | GSK3BCA1CA2RAB9ANPC1 | |
| SCHEMBL5737219 | 0.78 | MMP2 (0.62) | GSK3BCA1CA2RAB9AALDH1A1 | |
| SCHEMBL3362638 | 0.78 | GSK3B (0.61) | GSK3BCA1CA2RAB9ANPC1 | |
| SCHEMBL11060488 | 0.78 | GSK3B (0.61) | GSK3BCA1CA2POLBRAB9A | |
| SCHEMBL28972816 | 0.77 | GSK3B (0.51) | GSK3BCA1CA2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |