Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9248072 | 0.89 | ACHE (0.41) | ACHEAOC3ACP3ALDH1A1MAPK1 | |
| SCHEMBL9687697 | 0.81 | AOC3 (0.39) | ACHEAOC3 | |
| SCHEMBL9688988 | 0.74 | CYP3A4 (0.42) | ALDH1A1MAPK1GAAHPGDMEN1 | |
| SCHEMBL26450916 | 0.74 | ACHE (0.41) | ACHEAOC3ACP3ALDH1A1MAPK1 | |
| SCHEMBL9687417 | 0.70 | AOC3 (0.41) | AOC3ACP3ALDH1A1HPGDMEN1 | |
| SCHEMBL8750604 | 0.70 | ACHE (0.50) | ACHEAOC3ACP3ALDH1A1MAPK1 | |
| SCHEMBL3980388 | 0.70 | ACHE (0.50) | ACHEAOC3ACP3ALDH1A1MAPK1 | |
| SCHEMBL99347 | 0.69 | ACHE (0.55) | ACHEAOC3ACP3ALDH1A1MAPK1 | |
| SCHEMBL29352930 | 0.69 | ACHE (0.55) | ACHEAOC3ACP3ALDH1A1MAPK1 | |
| SCHEMBL29378635 | 0.69 | ACHE (0.55) | ACHEAOC3ACP3ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399284-B1 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0399284-A2 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |