Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNG | P07510 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687568 | 0.82 | PNMT (0.39) | AOC3PNMTACP3MEN1KMT2A | |
| SCHEMBL9248072 | 0.81 | ACHE (0.41) | AOC3ACP3MEN1KMT2AALDH1A1 | |
| SCHEMBL10442439 | 0.79 | AOC3 (0.46) | AOC3PNMTACP3OPRK1OPRM1 | |
| SCHEMBL9688011 | 0.79 | ADRB1 (0.53) | OPRK1OPRM1ADRB2ADRB1ADRB3 | |
| SCHEMBL9686706 | 0.79 | IDO1 (0.39) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9688924 | 0.79 | ADRB1 (0.30) | ADRB1 | |
| SCHEMBL9687872 | 0.79 | AOC3 (0.41) | AOC3SLC6A2SLC6A4 | |
| SCHEMBL8097006 | 0.77 | TAAR1 (0.40) | AOC3MEN1KMT2ASLC6A4CYP2C19 | |
| SCHEMBL11540939 | 0.76 | PNMT (0.46) | AOC3PNMTACP3MEN1KMT2A | |
| SCHEMBL18682090 | 0.76 | PNMT (0.46) | AOC3PNMTACP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |