Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.38 |
| ▸ | ITGAM | P11215 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246322 | 0.93 | TMPRSS15 (0.35) | ITGB3ITGA2B | |
| SCHEMBL9254859 | 0.89 | ITGB3 (0.42) | ITGB3ITGA2BITGAVITGB2ITGAM | |
| SCHEMBL9255479 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BITGAVITGB2ITGAM | |
| SCHEMBL9247579 | 0.87 | ITGB3 (0.40) | ITGB3ITGA2BITGB2ITGAM | |
| SCHEMBL9255713 | 0.87 | ITGB3 (0.41) | ITGB3ITGA2BITGAVITGB2ITGAM | |
| SCHEMBL9255743 | 0.85 | ITGB3 (0.40) | ITGB3ITGA2BITGAVITGB2ITGAM | |
| SCHEMBL9571132 | 0.84 | ITGB3 (0.36) | ITGB3ITGA2BITGAVITGB2ITGAM | |
| SCHEMBL9252066 | 0.83 | TMPRSS15 (0.36) | ITGB3ITGA2BITGAV | |
| SCHEMBL9255921 | 0.82 | ITGB3 (0.40) | ITGB3ITGA2BITGB2ITGAM | |
| SCHEMBL9255320 | 0.82 | TMPRSS15 (0.35) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |