Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.58 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6849115 | 0.88 | ALDH1A1 (0.50) | PARP10PARP15SRD5A2KDM4EALDH1A1 | |
| SCHEMBL7654088 | 0.86 | PARP10 (0.58) | PARP10PARP15SRD5A2RXRARXRB | |
| SCHEMBL10883326 | 0.86 | NR4A1 (0.63) | PARP10PARP15SRD5A2RXRARXRB | |
| SCHEMBL29464083 | 0.85 | ALDH1A1 (0.63) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL720128 | 0.85 | ALDH1A1 (0.63) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL17267881 | 0.85 | ALDH1A1 (0.63) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL29935746 | 0.83 | ALDH1A1 (0.65) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL29462465 | 0.83 | ALDH1A1 (0.65) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL335539 | 0.83 | ALDH1A1 (0.65) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL565006 | 0.82 | MEN1 (0.55) | PARP10KDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368006-B1 | Copolymers containing polybenzoxazole polybenzothiazole and polybenzimidazole moieties | DOW CHEMICAL CO (US) | 1995-04-05 | — | — | EP | disclosed |
| US-5151489-A | Block copolymers for compression molding to form fibers, films and laminates | THE DOW CHEMICAL COMPANY (US) | 1992-09-29 | — | — | US | disclosed |
| US-5110894-A | Thermoplastic films and fibers of high strength and thermal stability | THE DOW CHEMICAL COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5098985-A | Block copolymers for films, fibers, laminates or compression moldings | THE DOW CHEMICAL COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0392008-A4 | COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES | — | 1991-09-04 | — | — | EP | disclosed |
| EP-0392008-A1 | COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES | THE DOW CHEMICAL COMPANY (US) | 1990-10-17 | — | — | EP | disclosed |
| EP-0368006-A2 | Copolymers containing polybenzoxazole polybenzothiazole and polybenzimidazole moieties | THE DOW CHEMICAL COMPANY (US) | 1990-05-16 | — | — | EP | disclosed |
| WO-1990003995-A1 | COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES | THE DOW CHEMICAL COMPANY (US) | 1990-04-19 | — | — | WO | disclosed |