SCHEMBL9251422

SCHEMBL9251422

C=CC(=O)OC(F)(F)C(F)CCCCCCCC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
THRB P10828 2/20 0.36
THRA P10827 1/20 0.36
FAAH O00519 7/20 0.35
CES1 P23141 5/20 0.35
CES2 O00748 4/20 0.35
GPR84 Q9NQS5 3/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10339368 1.00 TSHR (0.41) TSHRMAPTHPGDZDHHC20ZDHHC2
SCHEMBL9302435 0.94 TSHR (0.46) TSHRMAPTHPGDZDHHC20ZDHHC2
SCHEMBL9301632 0.89 TSHR (0.39) TSHRHPGDTHRBHSD17B10
SCHEMBL31414416 0.85 ALDH1A1 (0.33) TSHR
SCHEMBL27697751 0.85 ALDH1A1 (0.33) TSHR
SCHEMBL9317303 0.84 TSHR (0.40) TSHRMAPTHPGDZDHHC20ZDHHC2
SCHEMBL31544632 0.83 ALDH1A1 (0.32) TSHR
SCHEMBL6365801 0.83 TSHR (0.38) TSHRMAPTHPGDZDHHC20ZDHHC2
SCHEMBL21581913 0.83 TSHR (0.38) TSHRMAPTHPGDZDHHC20ZDHHC2
SCHEMBL28585678 0.83 ALDH1A1 (0.33) TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0300661-B1 Reflection-preventive pellicle film and process for preparation thereof MITSUI PETROCHEMICAL IND (JP) 1995-09-13 EP disclosed
US-5059451-A Coating with a cellulose derivative; rotational film-forming; drying; coating film with a solution of polyfluoro(meth)acrylate; high light transmission; good adhesion MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-22 US disclosed
US-4966813-A OF CELLULOSE DERIVATIVE AND A LAYER OF POLYFLUORO(METH) ACRYLATE FORMED ON BOTH SURFACES MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-10-30 US disclosed
EP-0300661-A2 Reflection-preventive pellicle film and process for preparation thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-01-25 EP disclosed