Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302435 | 0.92 | TSHR (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9251422 | 0.89 | TSHR (0.41) | TSHRHPGDTHRBHSD17B10 | |
| SCHEMBL10339368 | 0.89 | TSHR (0.41) | TSHRHPGDTHRBHSD17B10 | |
| SCHEMBL9304290 | 0.87 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3132072 | 0.86 | ALDH1A1 (0.35) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL9312011 | 0.85 | TSHR (0.36) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28585678 | 0.83 | ALDH1A1 (0.33) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL31544632 | 0.80 | ALDH1A1 (0.32) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL63735 | 0.80 | TSHR (0.33) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL5511003 | 0.80 | TSHR (0.33) | TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336582-A | Electrophotographic image formation comprising an arylamine in a charge transport layer and an encapsulated toner | FUJI XEROX CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |
| US-5300388-A | Toner for electrophotography and process for producing the same | FUJI XEROX CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |