Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA3 | P07451 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA6 | P23280 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311483 | 0.87 | TAS1R3 (0.60) | ALDH1A1HPGDGAACA2KDM4E | |
| SCHEMBL178096 | 0.85 | ALDH1A1 (0.66) | CYP2D6ALDH1A1HPGDGAAMAOB | |
| SCHEMBL1287537 | 0.85 | ALDH1A1 (0.66) | CYP2D6ALDH1A1HPGDGAAMAOB | |
| SCHEMBL31367874 | 0.85 | CYP2D6 (0.59) | CYP2D6ALDH1A1HPGDGAAMAOB | |
| Hydrochloric Acid SCHEMBL11747973 | 0.84 | ALDH1A1 (0.64) | CYP2D6ALDH1A1HPGDGAAMAOB | |
| SCHEMBL4450673 | 0.84 | KDM4E (0.67) | CYP2D6ALDH1A1HPGDGAAMAOB | |
| SCHEMBL6240000 | 0.81 | CYP2D6 (0.70) | CYP2D6ALDH1A1HPGDGAASLC16A3 | |
| SCHEMBL11829416 | 0.80 | ALDH1A1 (0.76) | ALDH1A1HPGDGAAMAOBSLC16A3 | |
| SCHEMBL16710581 | 0.80 | CYP2D6 (0.57) | CYP2D6ALDH1A1HPGDGAAMAOB | |
| SCHEMBL11110472 | 0.80 | HPGD (0.56) | CYP2D6ALDH1A1HPGDGAAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464856-A | Arylmethylenyl derivatives of imidazolidinones useful as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1995-11-07 | — | — | US | disclosed |
| US-5306822-A | Mono-, di- or tri-methoxyphenylmethylene-2-thioxo-4-oxazolidinone as antihistamines | WARNER-LAMBERT COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5208250-A | Known and selected novel arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and anti-inflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0343643-A2 | Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents | WARNER-LAMBERT COMPANY (US) | 1989-11-29 | — | — | EP | disclosed |
| US-4542222-A | Benzimidazoles | CIBA-CEIGY CORPORATION (US) | 1985-09-17 | — | — | US | disclosed |
| US-4360679-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1982-11-23 | — | — | US | disclosed |
| US-4250317-A | OPTICAL BRIGHTENERS; FLUORESCENT DYES; TEXTILES; DETERGENTS | CIBA-GEIGY CORPORATION (US) | 1981-02-10 | — | — | US | disclosed |
| US-4146725-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1979-03-27 | — | — | US | disclosed |
| US-4009994-A | Process and product of optical brightening with quaternized benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1977-03-01 | — | — | US | disclosed |
| US-3940417-A | Quaternised benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |