SCHEMBL9251719

SCHEMBL9251719

CN1C(C)(C)CC(C(C(=O)O)=C(C(=O)O)C2CC(C)(C)N(C)C(C)(C)C2)CC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
APLNR P35414 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9251711 1.00 CYP2C19 (0.38) CYP2C19TSHRNFKB1APLNR
SCHEMBL10707935 1.00 CYP2C19 (0.38) CYP2C19TSHRNFKB1APLNR
SCHEMBL8849641 0.84 TSHR (0.32) CYP2C19TSHRNFKB1APLNR
SCHEMBL12110903 0.82 APLNR (0.58) CYP2C19TSHRNFKB1APLNR
SCHEMBL6676053 0.81 SMN1; SMN2 (0.38) CYP2C19TSHRNFKB1APLNR
SCHEMBL918603 0.78 TSHR (0.35) CYP2C19TSHRNFKB1APLNR
SCHEMBL11285730 0.74 APLNR (0.31) APLNR
SCHEMBL18534068 0.72 TSHR (0.33) CYP2C19TSHRNFKB1APLNR
SCHEMBL11164911 0.72 BRD4 (0.43) CYP2C19
SCHEMBL13979296 0.72 TSHR (0.37) CYP2C19TSHRNFKB1APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4404301-A Polymeric light stabilizers having at least one 2,2,6,6-tetraalkyl piperidyl group and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-09-13 US claimed
US-5457199-A 1,3,5-triazinyl derivatives; especially for polypropylene fibers CIBA-GEIGY CORPORATION (US) 1995-10-10 US disclosed
EP-0065655-B1 POLYMERIC LIGHT STABILIZERS HAVING AT LEAST ONE 2,2,6,6-TETRAALKYL PIPERIDYL GROUP AND SYNTHETIC RESIN COMPOSITIONS CONTAINING THE SAME ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1988-12-07 EP disclosed
US-4540728-A Diallyl-1,3,5-triazino-4-(2,2,6,6-tetramethyl piperidyl) amines as monomers and polymers and stabilized synthetic resin compositions ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1985-09-10 US disclosed
US-4499220-A Copolymer light stabilizers having at least one 2,2,6,6-tetraalkyl piperidyl group and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1985-02-12 US disclosed
US-4487900-A PHOTOSTABILITY ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1984-12-11 US disclosed
US-4404301-A Polymeric light stabilizers having at least one 2,2,6,6-tetraalkyl piperidyl group and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-09-13 US disclosed
US-RE31343-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
EP-0069871-A2 Copolymer light stabilizers having at least one 2,2,6,6-tetraalkyl piperidyl group and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1983-01-19 EP disclosed