Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707935 | 0.84 | CYP2C19 (0.38) | TSHRNFKB1CYP2C19APLNR | |
| SCHEMBL9251719 | 0.84 | CYP2C19 (0.38) | TSHRNFKB1CYP2C19APLNR | |
| SCHEMBL9251711 | 0.84 | CYP2C19 (0.38) | TSHRNFKB1CYP2C19APLNR | |
| SCHEMBL11173651 | 0.73 | TSHR (0.32) | TSHRNFKB1CYP2C19APLNR | |
| SCHEMBL12110903 | 0.72 | APLNR (0.58) | TSHRNFKB1CYP2C19APLNR | |
| SCHEMBL10193608 | 0.71 | CES2 (0.36) | — | |
| SCHEMBL6676053 | 0.71 | SMN1; SMN2 (0.38) | TSHRNFKB1CYP2C19APLNR | |
| SCHEMBL305181 | 0.69 | CES2 (0.34) | — | |
| SCHEMBL164998 | 0.69 | CES2 (0.39) | TSHR | |
| SCHEMBL305183 | 0.69 | CES2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499581-B1 | Stabilized polymer composition | CIBA GEIGY AG (CH) | 1997-07-09 | — | — | EP | disclosed |
| EP-0479725-B1 | Stabilized styrene copolymers containing elastomer particles | CIBA GEIGY AG (CH) | 1995-04-26 | — | — | EP | disclosed |
| EP-0337431-B1 | STABILIZED STYRENE COPOLYMER COMPRISING ELASTOMER PARTICLES | CIBA-GEIGY AG (CH) | 1993-06-23 | — | — | EP | disclosed |
| EP-0499581-A1 | Stabilized polymer composition | CIBA-GEIGY AG (CH) | 1992-08-19 | — | — | EP | disclosed |
| EP-0479725-A2 | Stabilized styrene copolymers containing elastomer particles | CIBA-GEIGY AG (CH) | 1992-04-08 | — | — | EP | disclosed |
| EP-0337431-A2 | Stabilized styrene copolymer comprising elastomer particles | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |