Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227363 | 1.00 | LMNA (0.39) | LMNAAPPCYP2C9 | |
| SCHEMBL771200 | 0.81 | CYP2C9 (0.35) | CYP2C9 | |
| SCHEMBL1721586 | 0.70 | — | — | |
| SCHEMBL16539999 | 0.69 | LMNA (0.39) | LMNAAPPCYP2C9 | |
| SCHEMBL30900624 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL15466854 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL9258790 | 0.69 | LMNA (0.62) | LMNAAPP | |
| SCHEMBL9235301 | 0.67 | LMNA (0.36) | LMNAAPP | |
| SCHEMBL278804 | 0.64 | — | — | |
| SCHEMBL1127899 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422365-A | Hydroxy, ether, and/or acyloxy substituted, saturated or partially unsaturated naphthalenes; for controlling insulin secretion | ADIR ET COMPAGNIE (FR) | 1995-06-06 | — | — | US | disclosed |