Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185529 | 0.89 | PDE4B (0.42) | SQORPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8479871 | 0.75 | MAPT (0.40) | SQORBRD4CHEK1AKT2BRD2 | |
| SCHEMBL12084050 | 0.69 | ALDH1A1 (0.45) | SQORBRD4CHEK1AKT2BRD2 | |
| SCHEMBL8474322 | 0.68 | MAPT (0.37) | SQORPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8478077 | 0.68 | — | — | |
| SCHEMBL8477183 | 0.66 | MAPT (0.36) | SQORPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8475027 | 0.66 | BRD4 (0.42) | BRD4CHEK1AKT2BRD2SMN1; SMN2 | |
| SCHEMBL14985964 | 0.66 | NPC1 (0.59) | SQORSMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL4724450 | 0.66 | NPC1 (0.39) | SQORSMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL10558033 | 0.65 | SMN1; SMN2 (0.31) | SMN1; SMN2GAAKMT2ACYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5461024-A | Herbicides | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-10-24 | — | — | US | disclosed |
| EP-0575435-A1 | THIOPHENESULFONYLUREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-12-29 | — | — | EP | disclosed |
| WO-1992016525-A1 | THIOPHENESULFONYLUREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-10-01 | — | — | WO | disclosed |