Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478355 | 0.84 | PTGS2 (0.42) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8474322 | 0.78 | MAPT (0.37) | MAPTSQORCASP1PDE4APDE4B | |
| SCHEMBL8185529 | 0.77 | PDE4B (0.42) | MAPTSQORCASP1PDE4APDE4B | |
| SCHEMBL8475027 | 0.77 | BRD4 (0.42) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8477183 | 0.76 | MAPT (0.36) | MAPTSQORCASP1PDE4APDE4B | |
| SCHEMBL8474956 | 0.76 | KDM4E (0.40) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9252162 | 0.75 | SQOR (0.40) | MAPTSQORCASP1PDE4APDE4B | |
| SCHEMBL8480049 | 0.74 | PDE4B (0.36) | MAPTSQORCASP1PDE4APDE4B | |
| SCHEMBL8478069 | 0.71 | HEXA (0.44) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8480173 | 0.68 | PTGS2 (0.44) | MAPTNPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |